منابع مشابه
Infusion rates for anaesthesia with propofol.
The infusion rate of propofol which would produce anaesthesia, when combined with nitrous oxide in oxygen, was studied in 75 fit unpremedicated patients undergoing body surface operations. The infusion rates were based on multiples of the median dose required to produce anaesthesia by intermittent injection in an additional 20 patients. The scatter of doses showed a right skew, for both intermi...
متن کاملPropofol and fentanyl anaesthesia for patients with low cardiac output state undergoing cardiac surgery: comparison with high-dose fentanyl anaesthesia.
We have compared the haemodynamic effects of an infusion of propofol 8 mg kg-1 h-1 followed by 4 mg kg-1 h-1 and fentanyl 15 micrograms kg-1 (group 1) with midazolam 3-6 mg and fentanyl 60 micrograms kg-1 (group 2) in patients with a low cardiac output state undergoing cardiac surgery. Heart rate was lower in group 1 throughout the period before cardiopulmonary bypass. There were no significant...
متن کاملPharmacokinetics of an infusion of propofol during cardiac surgery.
We have measured whole blood concentrations and pharmacokinetics of propofol administered as a constant rate infusion during cardiac surgery. Ten patients undergoing elective cardiac surgery involving cardiopulmonary bypass (seven myocardial revascularization and three aortic valve surgery) received a continuous infusion of propofol 4 mg kg-1 h-1 to supplement alfentanil analgesia. Whole blood ...
متن کاملTarget-controlled infusion of propofol in dogs--evaluation of four targets for induction of anaesthesia.
Four groups of 20 dogs were anaesthetised by means of target-controlled infusions of propofol designed to achieve 2.5 microg/ml, 3.0 microg/ml, 3.5 microg/ml or 4.0 microg/ml of propofol in blood. The dogs' pulse rate and respiratory rate were recorded before premedication and induction, immediately after endotracheal intubation and three and five minutes later (times 0, 3 and 5, respectively),...
متن کاملComparison of target controlled infusion and total intravenous anaesthesia with propofol and remifentanil for lumbar microdiscectomy.
BACKGROUND Propofol is often combined with remifentanil for induction and maintenance of total intravenous anaesthesia. Target-controlled infusion (TCI) permits adapting infusion to pharmacokinetic models. In this study we compared depth of anaesthesia, haemodynamic variables and times to recovery in patients scheduled for lumbar microdiscectomy and receiving either manually controlled (group I...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1989
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1989.tb09276.x